RxConnected Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Available 7 Days a Week


Express shipping

May be available upon request

Lowest Price, Guaranteed

match price or beat it by 10% *

Life-Time Free shipping

Find out if you're eligible!

  • Delivery time is between 8-14 business days.
  • Express shipping may be available upon request

What is Protopic Ointment?

Protopic Ointment is a prescription medication that is used to treat eczema. Protopic contains the macrolide immunosuppressant drug tacrolimus and works to slow down the growth of eczema by decreasing cell activity in the body’s immune system.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Wash your hands before applying this medication unless you are using it to treat your hands.
  • Apply a thin layer of Protopic Ointment to the affected skin area.
  • Stop using this medication after your symptoms have cleared. Speak to your doctor if your symptoms have not improved after six weeks of use.
  • Do not cover the affected area with a bandage.
  • Avoid swimming, showering, or bathing immediately after applying this medication.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • Your medical history particularly of skin cancer, skin infections, skin disorders, kidney disease, a weak immune system, or swelling, irritation, or redness on large areas of skin.
  • If you are pregnant or planning pregnancy.

You should also know:

  • This medication can affect your sensitivity to sunlight. Avoid sunlight, sunlamps, and tanning beds and wear protective clothing while outdoors. Do not apply sunscreen to the affected areas.
  • Protopic Ointment can weaken your immune system. Avoid people with infections such as chickenpox.
  • This medication passes into breast milk and can harm a nursing infant.

Side Effects of Protopic Ointment

Common side effects of Protopic Ointment include but are not limited to:

  • Flu symptoms including sneezing, stuffy nose, or sore throat.
  • Headaches.
  • Acne.
  • Increased sensitivity to temperatures.
  • Skin redness.
  • Mild stinging, itching, or burning where applied.

Get medical help if you have any of the following side effects of tacrolimus:

  • Severe stinging, burning, soreness, or itching where applied.
  • Crusting or redness around hair follicles.
  • Swollen glands.
  • Signs of skin infection including itching, swelling, redness, or oozing.
  • Symptoms of an allergic reaction such as difficulty breathing, hives, or swelling in your face, lips, or throat.


What should I do if I miss a dose of Protopic Ointment?

If you miss a dose of Protopic Ointment, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the strength of Protopic Ointment?

Protopic Ointment is available in a strength of 0.03%. Generic Protopic Ointment is known as tacrolimus ointment and is available in a strength of 0.1%.

Hear From People Like You

Don't just take our word, listen to real customers whose lives have changed for the better.

Real People, Trustworthy Reviews

See what others are saying about their experience!

Bernice R

March 23, 2023

I am very pleased with RX Connected. My conversations with everyone there has been positive and I really appreciate your quick response if I have a question.

MaryJean P

October 26, 2022

I really appreciate the reminders when I am due for refills. The staff are efficient and courteous.

Nancy S

October 7, 2022

Your service has been amazing!


October 1, 2022

Considering conditions in parts of the world today delivery was as usual. Meds arrived in the normal amount of time despite traveling distance.


September 14, 2022

The experiences I have had with Rx Connected have always been very positive. The representatives are always polite and clear with the instructions. I especially appreciate the calls I get explaining any delay or change in delivery. Thank you so much.

Joyce W

September 7, 2022

I’m always happy with your service.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.