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Activella (estradiol and norethindrone) is an oral medication that contains forms of the female hormones estrogen and progesterone. Activella used to treat symptoms of menopause and prevent osteoporosis in menopausal women.
Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.
Do not use Activella if you’ve had a hysterectomy, heart attack, stroke, blood clot, or certain cancers (breast, uterine, cervial).
Long-term use can increase your risk of developing breast, uterine, or ovarian cancer.
Activella can increase your risk of stroke, blood clots, and heart attack. These risks are increased in women who smoke, are overweight, and those with high blood pressure, high cholesterol, or diabetes.
Before taking Activella, inform your doctor if you have any of the following:
Common side effects of Activella include:
Contact your doctor if you experience these more serious side effects:
How long should I take Activella for?
You should take hormone therapies like Activella for the shortest amount of time possible. Your doctor will re-evaluate your needs every few months, and may consider switching you to a topical form of estrogen therapy.