1. Strength

0.5/0.1mg1/0.5mg

2. Quantity

Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

What is Activella?

Activella (estradiol and norethindrone) is an oral medication that contains forms of the female hormones estrogen and progesterone. Activella used to treat symptoms of menopause and prevent osteoporosis in menopausal women.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Take once daily, with or without food.
  • Try to take at the same time each day.
  • Self-examine your breasts on a monthly basis and have an annual mammogram while taking Activella.
  • Speak to your doctor if your condition does not improve.

Cautions

Do not use Activella if you’ve had a hysterectomy, heart attack, stroke, blood clot, or certain cancers (breast, uterine, cervial).

Long-term use can increase your risk of developing breast, uterine, or ovarian cancer.

Activella can increase your risk of stroke, blood clots, and heart attack. These risks are increased in women who smoke, are overweight, and those with high blood pressure, high cholesterol, or diabetes.

Before taking Activella, inform your doctor if you have any of the following:

  • Heart, liver, kidney, or gallbladder disease
  • Seizures
  • Asthma
  • Migraines
  • Lupus
  • Porphyria
  • Thyroid problems
  • High blood calcium
  • Angioedema

Side Effects

Common side effects of Activella include:

  • Changes in menstrual periods, vaginal itching or discharge
  • Breast pain
  • Nausea, bloating, vomiting, cramps
  • Headache
  • Thinning hair
  • Swelling and weight gain

Contact your doctor if you experience these more serious side effects:

  • Heart attack symptoms – spreading chest pain or pressure, nausea, sweating
  • Signs of a blood clot – shortness of breath, stabbing chest pain, coughing blood, sudden vision loss, pain or warmth in legs
  • High blood calcium – nausea, constipation, vomiting, increased thirst and urination, reduced energy, weakness, bone pain
  • Breast lump
  • Jaundice
  • Swollen, tender abdomen
  • Signs of stroke – numbness or weakness, slurred speech, severe headache, vision and balance problems

FAQs

How long should I take Activella for?

You should take hormone therapies like Activella for the shortest amount of time possible. Your doctor will re-evaluate your needs every few months, and may consider switching you to a topical form of estrogen therapy. 

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

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Reordering is always so easy, and I think my order arrived the next day!
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I have nothing but a positive experience with you, everyone is so nice and helpful. My order comes in time even with Covid. I am very happy!
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Great customer service and prompt delivery, thanks so much!
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Orders are prompt and notification is on time for delivery
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Excellent service
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Agent was very knowledgeable.
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Good communication on order.
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I appreciated when the RX Connected customer service gave me a “reminder call” when it was time for me to get my next refill of medication. That was definitely a great help to me !!!!
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Your people are nice to talk to.
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Overall the experience was positive. it did take about month to get here and the package was in pretty damaged, but the product was not affected.
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