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Arava (leflunomide) is used to treat the symptoms of rheumatoid arthritis. Leflunomide helps to reduce pain, swelling and joint damage enabling you to move better. Arava works by weakening your immune system which decreases inflammation.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

• Arava should be taken by mouth and can be taken with or without food. It is typically prescribed to be taken once a day.
• Your doctor may direct you to take a higher dosage for the initial three days of treatment.
• After you stop taking Arava, you may be prescribed to take cholestyramine to help remove leflunomide from your body.
• Tell your doctor if your condition persists or worsens.

Tell your doctor and pharmacist:

• About your drug and other allergies.
• If you take any other prescription or over-the-counter medications.
• Your medical history particularly of liver disease, hepatitis, severe infections, kidney disease, nerve problems, tuberculosis, a weak immune system or bone marrow disorder.

You should also know:

• You will need a negative pregnancy test before starting this treatment. Arava must not be used during pregnancy. Ask your doctor about methods of birth control.
• You should not breast-feed while taking Arava.
• After you stop taking Arava, you may be prescribed to take cholestyramine to help remove leflunomide from your body.

Common side effects of Arava include but are not limited to:

• Diarrhea or nausea.
• Dizziness.

Get medical help if you have any of the following side effects of Arava:

• Any rash. Leflunomide commonly causes a mild unserious rash. However, you may not be able to tell it apart from a rash which is a sign of a severe allergic reaction.
• Raised blood pressure.
• Signs of infections such as fever, chills, lymph nodes or a persistent sore throat.
• Cough.
• Numbness or tingling of your hands or feet.
• Hair loss.
• Fast or pounding heartbeat.
• Muscle cramp or pain.
• Chest pain.
• Vision changes.
• Increased thirst or urination.
• Mental or mood changes.
• Unusual growths or lumps.
• Unexplained weight loss.
• Unusual tiredness.
• Easy bruising or bleeding.
• Symptoms of an allergic reaction such as difficulty breathing, hives or swelling in your face, lips or throat.

What should I do if I miss a dose of Arava?

If you miss a dose of Arava, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the generic alternative to Arava?

Generic Arava is known as leflunomide and is also available in 10mg and 20mg. Only brand name Arava is available in 100mg strength.