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What is Asacol?

Asacol (mesalamine) is a drug that prevents inflammation and is used to treat inflammatory bowel disease including ulcerative colitis. It may also be used long-term to prevent the symptoms of these conditions from recurring.

Always follow your doctor’s instructions and use Asacol exactly as prescribed.

• Take with a full glass of water, with or without food.
• Asacol tablets have an enteric coating to protect your stomach. Swallow whole, and don’t crush, break, or chew the tablet.
• Take your full prescription of Asacol even if you feel better before the end of your treatment.
• Tell your doctor if you find undissolved tablets in your stool.

Before taking Asacol, inform your doctor if you have any of the following conditions:

• Liver or kidney disease
• Heart failure
• Pyloric stenosis
• Allergy to sulfasalazine

Tell your doctor if you are pregnant, planning pregnancy or breast feeding.

Asacol can cause you to have unusual results in some medical tests. Tell all of your doctors that you take this medication.

Call your doctor if you find undissolved tablets in your stool.

Common side effects of Asacol include:

• Headache
• Abdominal discomfort
• Belching
• Fatigue

Serious side effects of mesalamine include:

• Aggravated ulcerative colitis
• Allergic reaction: hives, swelling of face and throat, difficulty breathing
• Fever
• Bloody diarrhea

Can I drink alcohol while taking Asacol?

Drinking alcohol shouldn’t create any negative interactions with Asacol. However, it may be a trigger for symptoms of IBD or UC.

What if I notice an Asacol tablet in my stool?

This may be simply the coating of the Asacol tablet, but you should inform your doctor if you find a tablet in your stool.

Can I take NSAIDs with Asacol?

Taking NSAIDs like aspirin or ibuprofen along with Asacol may increase the risk of kidney damage. These pain relievers can also increase the risk of gastrointestinal bleeding. Check with your doctor before taking NSAIDs.