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What is Cardene?

Cardene, also known as nicardipine, is a medication used to treat high blood pressure (hypertension). Nicardipine can also be used to prevent chest pains and lower your risk for heart attack. Nicardipine is a calcium channel blocker that works by relaxing blood vessels so the heart does not have to pump as hard. Chest pain is controlled by increasing the supply of blood and oxygen to the heart.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • This medication is typically taken by mouth, 3 times a day with or without food.
  • Take your dosage at the same time each day for the most benefit.
  • Swallow the extended-release capsules whole, do not split, chew, or crush the capsules.
  • Most people with high blood pressure do not feel sick, so do not stop taking this drug even if you feel well.
  • Tell your doctor if your condition worsens, your blood pressure increases, or your chest pain is more severe.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • If you have aortic stenosis (a structural heart problem).
  • If you have a medical history of liver or kidney disease.

You should also know:

  • Consuming alcohol or marijuana can increase side effects of dizziness.
  • This drug can be taken during pregnancy when clearly needed. It is unknown if the drug passes into breast milk. Consult your doctor to discuss the risks and benefits of pregnancy or breast-feeding on this drug.

Side effects of Cardene

Common side effects of Cardene include but are not limited to:

  • Dizziness
  • Lightheadedness (get up slowly when rising from a lying position to prevent this side effect)
  • Headache
  • Flushing
  • Swelling of the ankles or feet

Get medical help if you have any of the following side effects of nicardipine.

  • Vision changes
  • Fainting
  • Irregular or pounding heartbeat
  • Worsening chest pain
  • Symptoms of a heart attack (chest/jaw/arm pain, shortness of breath)


How long does it take for Cardene to take effect?

The initial onset of the medication occurs in about 45 minutes. Once you begin taking Cardene, you will likely reach a steady state after about 50 hours. The absorption of Cardene depends on several factors, but consult your doctor if your condition does not improve after a few days of using this drug.

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March 23, 2023

I am very pleased with RX Connected. My conversations with everyone there has been positive and I really appreciate your quick response if I have a question.

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October 26, 2022

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October 1, 2022

Considering conditions in parts of the world today delivery was as usual. Meds arrived in the normal amount of time despite traveling distance.


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A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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