Canadian Pharmacy > DDAVP Nasal Spray (Desmopressin)
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DDAVP Nasal Spray (Desmopressin)
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1 x 2.5ml (25 doses) $49.00 BUY
2 x 2.5ml (50 doses) $84.00 BUY
3 x 2.5ml (75 doses) $123.00 BUY
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Desmopressin is a synthetic, man-made version of a naturally-occurring hormone in the human pituitary gland. This hormone affects blood pressure, kidney function, and how the body uses water. It treats central cranial diabetes insipidus, as well as the heightened thirst and urination that results from head surgery or head trauma.



Carefully follow your doctor’s directions and read any attached information with the drug. Dosage may be adjusted occasionally. Regular medical testing may be necessary. If you use this drug to control bleeding, get medical attention if desmopressin does not control bleeding.

When you first start the medicine, prime the spray by testing four to five sprays. Prime again if the spray hasn’t been used in three days or longer. Keep track of how many times you spray, as each bottle contains a specific number of sprays. The medicine should be thrown away after this number is reached, even if there appears to be some left over.

Limit how much fluid you consume. Overconsumption of water can cause sodium loss as well as life-threatening electrolyte imbalance. This is especially important in older patients and children.

If you miss a dose, take it when you remember, but skip the missed dose if it’s almost time for your next one.

Desmopressin should be stored at room temperature away from heat and moisture in an upright position. Unopened Noctiva should be stored in the fridge, but after opening it, store it at room temperature to be used within 60 days. DDAVP Rhinal Tube should also be stored in the fridge, but not frozen, although closed bottles can be kept at room temperature for up to three weeks.

Do not use desmopressin past the expiration date.


Don’t take DDAVP if you are allergic to desmopressin. DDAVP may not work as well if you have swelling or scarring inside your nose or if you have nasal or sinus problems.

If you have any of the following conditions, you may not be able to use desmopressin nasal: the history of low sodium levels, uncontrolled hypertension, congestive heart failure, kidney disease, SIADH, fever, infection, vomiting, diarrhea, or a condition that causes excessive thirst, dehydration, or electrolyte imbalance.

Let your doctor know if you’ve experienced: nasal problems like congestion; a psychologic disorder that causes extreme or unusual thirst; an infection with fever, vomiting, or diarrhea; inability to urinate or kidney disease; head trauma or brain tumor; diabetes; or cystic fibrosis.

Desmopressin’s effect on pregnancy is unknown. Tell your doctor if you become pregnant or plan to and if you breast-feed. This medicine is not meant to treat excessive urination during pregnancy.

Side Effects

Call your doctor if you experience: vomiting or diarrhea, fever, or unusually excessive sweating. You are at higher risk of dehydration, which may lead to, severe low blood pressure or severe electrolyte imbalance.

Get emergency attention if you suspect an allergic reaction, and if you experience signs of low sodium, rapid weight gain, swelling in ankles and feet, convulsions, or nasal problems. Low sodium may appear as headaches, drowsiness, confusion, vomiting, restlessness, weakness, muscle pain, and loss of appetite.

Other common side effects include: nasal discomfort, sore throat, cough, dizziness, increased blood pressure, back pain, headaches, flushing, insomnia, itchy eyes, and light sensitivity.

Not all possible side effects and drug interactions are provided here.


Can desmopressin interact harmfully with other things?

Yes. Inform your doctor of other drugs you take, especially if you take diuretics, steroid medications, other nasal medications, antidepressants, bladder or urinary drugs, cold or allergy drugs, heart or blood pressure medicine, psychiatric medications, seizure medicine, and NSAIDs. Also tell your doctor if you use OTC drugs, herbs, supplements, and vitamins.

IMPORTANT NOTE: The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.
IMPORTANT NOTE: Please note that not all medications, including any referenced on this page, are dispensed from our affiliated Canadian pharmacy. The medications in your order may be filled and shipped from an approved International fulfillment center located in a country other than Canada. In addition to dispensing medications from our Canadian pharmacy, medication orders are also filled and shipped from international fulfillment centers that are approved by the regulatory bodies from their respective countries. Medication orders are filled and shipped from approved fulfillment centers around the world including, but not limited to, Canada, Singapore, United Kingdom, New Zealand, Turkey, Mauritius, India, Australia, and the United States. The items in your order may be filled and shipped from any one of the above jurisdictions. The products are sourced from various countries including, but not limited to, Canada, United Kingdom, New Zealand, Turkey, India, Australia, and the United States. All of our affiliated fulfillment centers have been approved by the regulatory bodies from their respective countries.

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What's the difference between generic drugs and brand name drugs?

What's the difference between the branded products you sell and the ones I get locally?
The branded drugs we sell are chemically and therapeutically no different from the ones you get in your local pharmacy. They both generally come from the same exact manufacturer. Generally, the main difference* is in the packaging and the price. Our packaging may be different from what you get locally, but we're also much cheaper.

* Other differences may include differences in trade name, form, and general appearance.

Why are there packaging differences?
Due to differences in government regulation, different countries have different packaging requirements. For example, a product in Canada (or any other country) will have different packaging than the same product in the US even though both drugs are chemically and therapeutically equivalent and are generally manufactured by the same exact company.

Why are your drugs so much cheaper?
Due to government price controls, medications from Canada and many other countries are often significantly cheaper than in the United States. Also, other countries may have more affordable generic versions of drugs, which may not yet be available in the US.

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