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Desowen lotion (desonide) is a steroid topical that prevents inflammation. It works by stopping your body from releasing certain inflammation-triggering substances.

When prescribed desonide lotion, you will likely be asked to apply it two to three times a day. Before applying it each time, wash your hands. Then, apply the lotion to your affected area by gently rubbing it in. Make sure to do this routine regularly for optimal results.


To raise your chances of getting the right reaction and avoiding unwanted side effects, do not use desonide lotion for anything that your doctor has not prescribed the medication for. Also, make sure to avoid getting the medication in your eyes, broken or infected skin, or open wounds. If any contact does happen, rinse the lotion off entirely with water.

Side Effects

It’s important to realize that Desowen lotion has the potential to cause desonide side effects. For instance, these desonide side effects can happen due to the medication’s steroid nature. As the steroid gets absorbed into the skin, the body can experience side effects related to the steroids. These can include blurry vision, uneven heartbeats, insomnia, weight gain, facial puffiness, and fatigue. If you notice any of these, stop using Desowen lotion and get in touch with your doctor right away.

You should do the same if you experience severe skin redness in the area where you’ve applied Desowen lotion or signs of a skin infection, such as swelling, redness, warmth, or oozing.

More common desonide side effects you may encounter involve stinging or burning treated skin, itching, dry skin, scaly skin, peeling skin, acne, rashes, stretch marks, the lightened color of treated skin, and folliculitis.


What is desonide cream used for?

The desonide cream or lotion is typically used to treat skin conditions that cause irritation, such as inflammation and itching. So doctors will generally prescribe desonide cream for allergic reactions, eczema, and psoriasis. However, other conditions could end up being treated by desonide cream as well.

Is desonide generic medication?

Yes. The brand-name equivalent is Desowen.

Will desonide interact with other drugs?

Luckily, it’s not common for desonide to interact poorly with medication that’s taken orally or via injection. However, there’s always a chance your medication could interact poorly with other types of medication. For more accurate information, talk with your doctor.

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