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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

What is Estrace?

Are you tired and frustrated with the cost of your prescription medications? By ordering with RXConnected, you can save up to 90% on the price of Estrace. We are a safe, convenient and affordable option to expensive drug prices. Order online or call us 7 days a week.

Estrace is a female hormone medication containing estradiol. Estrace is used to reduce the symptoms of menopause including hot flashes and vaginal dryness. Estradiol may also be prescribed to prevent osteoporosis in menopausal women and to replace estrogen in women with conditions that cause a lack of natural estrogen in women. Estrace may also be used as part of cancer treatment for both men and women.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Take Estrace orally with or without food. Taking Estrace with food or right after a meal may help to prevent stomach upset.
  • Your doctor may want to check your progress regularly while taking this medication.
  • Self-examine your breasts for lumps each month and have annual mammograms while taking Estrace.
  • Estrace is most effective when it is taken regularly. Try to take it at the same time each day.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • Your medical history particularly of unusual vaginal bleeding, liver disease, heart attack, stroke, blood clots, heart problems, hereditary blood disorders, cancer, liver problems, jaundice, kidney disease, gallbladder disease, asthma, epilepsy, seizures, migraines, lupus, endometriosis, uterine fibroid tumours, hereditary angioedema, porphyria, thyroid disorders or high levels of calcium in your blood.
  • If you are breastfeeding.
  • If you will be having or have recently had surgery or if you will be confined to a bed or chair for a period of time. These conditions may increase the chance of blood clots.

You should also know:

  • Estrace should not be used during pregnancy.
  • You should not smoke while taking this medication. Estrogens combined with smoking can increase the risk of stroke, heart attack, blood clots and high blood pressure particularly in women over 35.

Estrace Side Effects

Common side effects of Estrace include but are not limited to:

  • Vaginal itching or discharge.
  • Changes to your menstrual periods.
  • Breakthrough bleeding.
  • Headache, back pain or breast pain.
  • Nausea, stomach cramps, vomiting or diarrhea.
  • Sleep problems.
  • Mood changes.
  • Weight gain.
  • Cold symptoms including sore throat, sinus pain or stuffy nose.

Get medical help if you have any of the following side effects of Estrace:

  • Stomach tenderness or swelling.
  • Unusual behavior, confusion or memory problems.
  • Jaundice.
  • Breast lumps.
  • Unusual vaginal bleeding or pelvic pain.
  • Signs of high levels of calcium in your blood including lack of energy, bone pain, muscle weakness, constipation, nausea, vomiting or increased thirst or urination.
  • Stroke symptoms including sudden severe headache, slurred speech, vision problems, balance problems or a sudden numbness or weakness especially to one side of the body.
  • Blood clot symptoms particularly stabbing chest pain, shortness of breath, sudden vision loss, coughing up blood or warmth in one or both legs.
  • Heart attack symptoms such as nausea, sweating, chest pain, chest pressure or a pain which spreads to your jaw or shoulder.
  • Symptoms of an allergic reaction such as difficulty breathing, hives or swelling in your face, lips or throat.


What should I do if I miss a dose of Estrace?

If you miss a dose of Estrace, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the generic alternative to Estrace?

Generic Estrace is known as estradiol and is available in the same 0.5mg, 1mg and 2mg strengths.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

I have had good experiences with RX Connected. Rich
Richard February 28, 2020

Real Customers, Honest Reviews

I placed my first order last November. The process is exactly as I was told. I emailed my information, and sent original copies to them. Every time I have refilled my medication the representative has been friendly,and knowledgeable. I called today inquiring about the current status of a refill. After a short time, the representative gave me the information I needed (so I wouldn't worry). I appreciate the savings, and the professionalism shown by all the employees I've had contact with via phone. Keep up the good work.
Alex February 27, 2020

Real Customers, Honest Reviews

Like most other people, my prescription was very expensive and not covered. I started looking and found this pharmacy. While it takes approximately a month to receive your script, it's worth it for the savings.
Margaret February 26, 2020

Real Customers, Honest Reviews

In the past, I had heard people talk about getting some of their prescriptions from Canada due to the high prices in the US. I never really considered it until after a local doctor suggested RX Connected for one of my recommended medications. The price for the medication here was very expensive and not covered by by Medicare drug supplement plan. I'm very grateful that he told me about RX Connected. I have since told several other people about RX Connected. After your doctor writes the initial prescription, you just send it in, and the process begins. They are careful, professional, and send me my medication by mail, on time, like clock-work. Thank you RX Connected!
Judy February 25, 2020

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Always very polite and helpful. I appreciate so much the reminders when it's time to renew my prescription! Thank you!
Betty February 21, 2020

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great thanks
Helen February 21, 2020

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Sheffield February 21, 2020

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Great service.
Joe February 21, 2020

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Patricia February 21, 2020

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Easy process and reasonable pricing . Both good reasons to use this company .
Terry October 25, 2019
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