RxConnected Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Available 7 Days a Week


Express shipping

May be available upon request

Lowest Price, Guaranteed

match price or beat it by 10% *

Life-Time Free shipping

Find out if you're eligible!

  • Delivery time is between 8-14 business days.
  • Express shipping may be available upon request

Buy Estring (Estradiol Vaginal Ring)

RXConnected makes buying Estring and other prescription and non-prescription medications simple and affordable. All of our medications are sent directly to you saving you hassle and time. RXConnected can help you to save 90% on the cost of your drugs. Order online or call us now.

What is Estring?

Estring is a vaginal ring used to treat menopausal vaginal changes including, itching, burning, dryness, and urinary discomfort. Estring is a soft, flexible ring which releases estrogen through the vaginal wall in a stable, consistent manner for 90 days. It contains estradiol, a form of the female sex hormone estrogen.

Always follow your doctor’s instructions and use Estring exactly as prescribed.

  • Wash your hands before and after inserting an Estring ring.
  • Squeeze the sides of the ring and insert it as high as possible into the vagina.
  • You should not be able to feel Estring once it’s inserted. If you can feel it, push it higher with a finger.
  • Leave Estring in place for 90 days. If it falls out, rinse with warm water and reinsert.
  • After 90 days, loop your finger through the ring and pull it out gently. Replace it with a new ring.
  • Self-examine your breasts for lumps each month and have a yearly mammogram.


Estring and other estradiol medications can increase your risk of blood clots, stroke, or heart attack. Long-term use has been linked to breast, uterine, and ovarian cancer.

Do not smoke while taking Estring. This will increase your risk of blood clots, stroke and heart attack.

Before taking Estring, inform your doctor if you have any of the following:

  • Liver or coronary artery disease
  • Bleeding disorders
  • History of stroke, heart attack, blood clots
  • Hormone related cancers or breast, uterine, or cervical cancer
  • Unusual vaginal bleeding

Estring Side Effects

Common side effects of Estring include:

  • Headache
  • Nausea, vomiting, bloating, cramps
  • Breast pain
  • Swollen hands and feet
  • Vaginal itching or discharge

Contact your doctor if you experience these more serious side effects:

  • Heart attack symptoms – chest pain spreading in your jaw or shoulder, nausea, sweating
  • Stroke – numbness or weakness on one side of the body, slurred speech, poor balance and coordination
  • Signs of a blood clot – shortness of breath, stabbing chest pain, coughing blood, sudden vision loss, pain or warmth in legs
  • Jaundice
  • Breast lumps
  • High blood calcium – muscle weakness, bone pain, lack of energy, increased thirst and urination, nausea, vomiting, constipation
  • Swelling or tender stomach
  • Unusual behavior, memory problems, confusion
  • Unusual vaginal bleeding, pelvic pain


Do I need to remove Estring during intercourse?

No. Estring can remain in place and shouldn’t cause discomfort during intercourse. If it falls out, rinse with warm water and replace.

How do I dispose of Estring?

Throw in a trash that pets and children don’t have access to. Do not flush Estring down the toilet.

Hear From People Like You

Don't just take our word, listen to real customers whose lives have changed for the better.

Real People, Trustworthy Reviews

See what others are saying about their experience!

Bernice R

March 23, 2023

I am very pleased with RX Connected. My conversations with everyone there has been positive and I really appreciate your quick response if I have a question.

MaryJean P

October 26, 2022

I really appreciate the reminders when I am due for refills. The staff are efficient and courteous.

Nancy S

October 7, 2022

Your service has been amazing!


October 1, 2022

Considering conditions in parts of the world today delivery was as usual. Meds arrived in the normal amount of time despite traveling distance.


September 14, 2022

The experiences I have had with Rx Connected have always been very positive. The representatives are always polite and clear with the instructions. I especially appreciate the calls I get explaining any delay or change in delivery. Thank you so much.

Joyce W

September 7, 2022

I’m always happy with your service.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.