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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

What is Estrogel?

Estrogel (estradiol) is a medication used to reduce symptoms of menopause including hot flashes and vaginal dryness, burning or irritation. Estrogel contains the female estrogen hormone estradiol. Estrogens are female sex hormones produced by the ovaries which regulate many body processes. Estrogel is absorbed through the skin and enters into your blood stream.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Only apply Estrogel to clean, dry and unbroken skin. Do not apply it to skin which is irritated or red. Never apply Estrogel to your breasts.
  • Before using this medication for the first time, prime it by depressing the pump for the number of times advised by the enclosed instructions and discard the unused gel.
  • Apply Estrogel to dry skin at the same time each day.
  • Press the pump down firmly and collect the Estrogel dose in the palm of your hand. Apply the gel to one arm, spreading it as thinly as possible over the entire area on the inside and outside of your arm from wrist to shoulder.
  • Wash your hands with soap and water after applying this medication.
  • Allow the gel to dry for five minutes before dressing. Estrogel is flammable. Do not smoke or go near an open flame until the medication has dried.
  • Apply Estrogel after a bath, shower or sauna. If you go swimming, leave as much time as possible between applying the medication and swimming.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • Your medical history particularly of abnormal vaginal bleeding, cancer, heart attack, stroke, blood clot, liver disease, bleeding disorder, blood clotting disorders, heart disease asthma, epilepsy, kidney disease, hereditary angioedema, endometriosis, thyroid disorder, lupus, migraines, gallbladder disease, diabetes, high blood pressure, high cholesterol or high levels of calcium in your blood.
  • If you have any other risk factors for coronary artery disease including smoking, being overweight, being over 40 or having a hysterectomy.

You should also know:

  • Estrogel should not be used during pregnancy.
  • Estradiol may increase your risk of uterine cancer. Tell your doctor immediately if you have any unusual vaginal bleeding.
  • Children should avoid contact with Estrogel and areas where Estrogel has been applied.
  • Estrogel should not be used if you are breast-feeding.

Side Effects of Estrogel

Common side effects of Estrogel include but are not limited to:

  • Breast pain.
  • Vaginal itching or discharge.
  • Light vaginal bleeding or spotting.
  • Changes to your menstrual periods.
  • Nausea or vomiting.
  • Bloating or stomach cramps.
  • Thinning scalp hair.

Get medical help if you have any of the following side effects of Estrogel:

  • Abnormal vaginal bleeding.
  • A lump in your breast.
  • Confusion or problems with your memory or concentration.
  • Signs of a blood clot in the lung including wheezing, chest pain, sudden cough, rapid breathing or coughing up blood.
  • Signs of a blood clot in your leg including pain, swelling, warmth or redness in one or both legs.
  • Symptoms of a stroke including sudden severe headache, slurred speech, problems with vision or balance or a sudden numbness or weakness especially on one side of your body.
  • Symptoms of liver problems such as nausea, itching, loss of appetite, dark urine, jaundice, upper stomach pain. Tiredness or clay-colored stools.
  • Heart attack symptoms including nausea, sweating, chest pain or pressure or a pain spreading to your jaw or shoulder.
  • Symptoms of an allergic reaction such as difficulty breathing, hives or swelling in your face, lips or throat.


What should I do if I miss a dose of Estrogel?

If you miss a dose of Estrogel, you should take it as soon as you remember. However, if you are more than twelve hours late, then skip your missed dose.

What else is Estrogel called?

Estrogel is also known as Oestrogel internationally. Oestrogel is the same brand name medication with a different name internationally and is not a generic alternative medication.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

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* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

I have had good experiences with RX Connected. Rich
Richard February 28, 2020

Real Customers, Honest Reviews

I placed my first order last November. The process is exactly as I was told. I emailed my information, and sent original copies to them. Every time I have refilled my medication the representative has been friendly,and knowledgeable. I called today inquiring about the current status of a refill. After a short time, the representative gave me the information I needed (so I wouldn't worry). I appreciate the savings, and the professionalism shown by all the employees I've had contact with via phone. Keep up the good work.
Alex February 27, 2020

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Like most other people, my prescription was very expensive and not covered. I started looking and found this pharmacy. While it takes approximately a month to receive your script, it's worth it for the savings.
Margaret February 26, 2020

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In the past, I had heard people talk about getting some of their prescriptions from Canada due to the high prices in the US. I never really considered it until after a local doctor suggested RX Connected for one of my recommended medications. The price for the medication here was very expensive and not covered by by Medicare drug supplement plan. I'm very grateful that he told me about RX Connected. I have since told several other people about RX Connected. After your doctor writes the initial prescription, you just send it in, and the process begins. They are careful, professional, and send me my medication by mail, on time, like clock-work. Thank you RX Connected!
Judy February 25, 2020

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Always very polite and helpful. I appreciate so much the reminders when it's time to renew my prescription! Thank you!
Betty February 21, 2020

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great thanks
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Sheffield February 21, 2020

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Great service.
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Patricia February 21, 2020

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Easy process and reasonable pricing . Both good reasons to use this company .
Terry October 25, 2019
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