RxConnected Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Available 7 Days a Week


Express shipping

May be available upon request

Lowest Price, Guaranteed

match price or beat it by 10% *

Life-Time Free shipping

Find out if you're eligible!

  • Delivery time is between 8-14 business days.
  • Express shipping may be available upon request

What is Glucophage XR?

Glucophage XR is a prescription medication that is used to improve blood sugar control in patients who have type 2 diabetes. Glucophage XR contains metformin and works by helping to restore the body’s response to insulin and by decreasing the amount of sugar produced by the liver. Glucophage XR should be taken as part of a diabetes treatment program that may also include diet and exercise.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Glucophage XR is typically taken once a day with the evening meal.
  • Swallow metformin ER whole without chewing or crushing.
  • Watch out for signs of low blood sugar. Eat or drink a fast-acting source of sugar if this occurs.
  • Glucophage XR may be prescribed as part of a diabetes treatment program that can also include diet and exercise.
  • Part of the Glucophage XR tablet may appear in your stool. This is normal.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • Your medical history particularly of kidney disease, liver disease, heart disease, congestive heart failure, metabolic acidosis, diabetic ketoacidosis, or high ketone levels in your blood or urine.
  • If you use insulin or any other diabetes medications.
  • If you need to have any type of x-ray or CT scan while taking Glucophage XR.
  • If you are pregnant. Your dosage may need to be changed during your trimesters.

You should also know:

  • Glucophage XR should not be used by anyone younger than 18.
  • Do not breast-feed while taking Glucophage XR.
  • This medication can stimulate ovulation in premenopausal women and increase the risk of unintended pregnancy.

Side Effects of Glucophage XR

Common side effects of Glucophage XR include but are not limited to:

  • Low blood sugar.
  • Diarrhea.
  • Nausea.
  • Upset stomach.

Get medical help if you have any of the following side effects of metformin.

  • Breathing trouble.
  • Slow or irregular heart rate.
  • Unusual muscle pain.
  • Dizziness or lightheadedness.
  • Feeling tired or very weak.
  • Vomiting.
  • Feeling cold.
  • Stomach pain.
  • Symptoms of an allergic reaction such as difficulty breathing, hives, or swelling in your face, lips, or throat.


What should I do if I miss a dose of Glucophage XR?

If you miss a dose of Glucophage XR, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What else is Glucophage XR called?

Glucophage XR is also known as Glumetza internationally. Glumetza is the same brand name medication with a different name internationally and is not a generic alternative medication. Generic Glucophage XR is called metformin ER.

Hear From People Like You

Don't just take our word, listen to real customers whose lives have changed for the better.

Real People, Trustworthy Reviews

See what others are saying about their experience!

Bernice R

March 23, 2023

I am very pleased with RX Connected. My conversations with everyone there has been positive and I really appreciate your quick response if I have a question.

MaryJean P

October 26, 2022

I really appreciate the reminders when I am due for refills. The staff are efficient and courteous.

Nancy S

October 7, 2022

Your service has been amazing!


October 1, 2022

Considering conditions in parts of the world today delivery was as usual. Meds arrived in the normal amount of time despite traveling distance.


September 14, 2022

The experiences I have had with Rx Connected have always been very positive. The representatives are always polite and clear with the instructions. I especially appreciate the calls I get explaining any delay or change in delivery. Thank you so much.

Joyce W

September 7, 2022

I’m always happy with your service.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.