Glucovance is a prescription medication that is used to control blood sugar levels in patients who have type 2 diabetes. Glucovance is a combination medication that contains glyburide and metformin. These medications work by lowering the amount of sugar produced by the liver and absorbed by the stomach and intestines. Glucovance should be taken as part of a diabetes treatment program that can also include exercise and diet.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

• Glucovance should be taken with meals.
• Drink plenty of liquids while taking this medication.
• Watch for signs of low or high blood sugar while taking Glucovance.
• Glucovance may be prescribed as part of a diabetes treatment program that may also include diet and exercise.

Tell your doctor and pharmacist:

• About your drug and other allergies.
• If you take any other prescription or over-the-counter medications.
• Your medical history particularly of kidney disease, liver disease, heart disease, heart attack, stroke, metabolic acidosis, diabetic ketoacidosis, or severe infections.
• If you need an x-ray or CT scan that uses a dye injection.
• If you drink alcohol.
• If you are pregnant or planning pregnancy. Your dosage may need to be changed and you may need to pause your treatment before giving birth.

You should also know:

• Do not breast-feed while taking Glucovance.
• Avoid drinking alcohol while taking Glucovance.

Common side effects of Glucovance include but are not limited to:

• Headaches.
• Upset stomach.
• Nausea.
• Diarrhea.
• Low blood sugar.

Get medical help if you have any of the following side effects of Glucovance.

• Signs of a heart problem including shortness of breath, swelling, or rapid weight gain.
• Signs of lactic acidosis including irregular heart rate, breathing problems, stomach pain, unusual muscle pain, vomiting, dizziness, weakness, tiredness, or feeling cold.
• Signs of severe hypoglycemia including stomach pain, seizures, confusion, blurred vision, sweating, extreme weakness, or speaking problems.
• Symptoms of an allergic reaction such as difficulty breathing, hives, or swelling in your face, lips, or throat.

What should I do if I miss a dose of Glucovance?

If you miss a dose of Glucovance, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the strength of Glucovance?

Both Glucovance and the generic alternative glyburide/metformin are available in a strength of 2.5mg/500mg. Only brand name Glucovance is available in a strength of 5mg/500mg.