1. Strength


2. Quantity

Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?

What is Pennsaid?

Pennsaid, also known as diclofenac, is a topical solution used to treat pain in the knees caused by osteoarthritis. This drug is only meant for the knee and should not be used on other parts of the body. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation.


Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Wash your hands before applying Pennsaid and wait for at least 30 minutes before bathing or showering.
  • Spread the solution over the front, back, and sides of the knee. Wait until it is dry before putting on clothes.
  • Wait until the area is dry before applying cosmetics, sunscreen, lotions, or other medication skin products on the same area you treat with Pennsaid.
  • Do not apply this medication to an open wound or area of infection, rash, or burn.
  • Do not cover treated skin with bandage or heating pad.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • If you have a medical history of heart disease, high blood pressure, high cholesterol, stomach ulcers, asthma, liver or kidney disease, or fluid retention.
  • If you are pregnant or breast-feeding.

You should also know:

  • This drug may increase your risk of fatal heart attack or stroke as well as intestinal bleeding.
  • Pennsaid should not be used for anyone younger than 18 years old.
  • It is not known if this drug passes into breast milk.
  • Diclofenac can affect ovulation and it can be harder to get pregnant while taking this drug.
  • Using Pennsaid in the last three months of pregnancy may harm the unborn baby.

Side effects of Pennsaid

Common side effects of Pennsaid include but are not limited to:

  • Burning, itching, or redness of the skin
  • Swelling
  • Soreness at the application site

Get medical help if you have any of the following side effects of diclofenac.

  • Diarrhea
  • Loss of appetite
  • Shivering or chills
  • Trouble sleeping
  • Vomiting
  • Blood in urine
  • Trouble breathing
  • Increased sensitivity of the skin to sunlight


What dosages are available for Pennsaid?

Pennsaid is available in generic and brand name 60 ml and 120 ml dosages.

What should I avoid while using Pennsaid?

It is important to avoid exposed treated skin to heat and sunlight. Avoiding alcohol to prevent the risk of stomach bleeding is also recommended. Ask your doctor before taking any cold or allergy medication.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

I have had good experiences with RX Connected. Rich
Richard February 28, 2020

Real Customers, Honest Reviews

I placed my first order last November. The process is exactly as I was told. I emailed my information, and sent original copies to them. Every time I have refilled my medication the representative has been friendly,and knowledgeable. I called today inquiring about the current status of a refill. After a short time, the representative gave me the information I needed (so I wouldn't worry). I appreciate the savings, and the professionalism shown by all the employees I've had contact with via phone. Keep up the good work.
Alex February 27, 2020

Real Customers, Honest Reviews

Like most other people, my prescription was very expensive and not covered. I started looking and found this pharmacy. While it takes approximately a month to receive your script, it's worth it for the savings.
Margaret February 26, 2020

Real Customers, Honest Reviews

In the past, I had heard people talk about getting some of their prescriptions from Canada due to the high prices in the US. I never really considered it until after a local doctor suggested RX Connected for one of my recommended medications. The price for the medication here was very expensive and not covered by by Medicare drug supplement plan. I'm very grateful that he told me about RX Connected. I have since told several other people about RX Connected. After your doctor writes the initial prescription, you just send it in, and the process begins. They are careful, professional, and send me my medication by mail, on time, like clock-work. Thank you RX Connected!
Judy February 25, 2020

Real Customers, Honest Reviews

Always very polite and helpful. I appreciate so much the reminders when it's time to renew my prescription! Thank you!
Betty February 21, 2020

Real Customers, Honest Reviews

great thanks
Helen February 21, 2020

Real Customers, Honest Reviews

Sheffield February 21, 2020

Real Customers, Honest Reviews

Great service.
Joe February 21, 2020

Real Customers, Honest Reviews

Patricia February 21, 2020

Real Customers, Honest Reviews

Easy process and reasonable pricing . Both good reasons to use this company .
Terry October 25, 2019
Read All Reviews
Write a Review