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How much does Premarin cost?

The cost of Premarin tablets is based on the strength that you order. Premarin is available in 0.3mg, 0.625mg and 1.25mg strengths. Buying your prescription medication with RxConnected is a safe, quick and affordable way to buy Premarin.

What is Premarin?

Premarin is prescribed to treat women with menopausal symptoms or who don’t produce enough hormones. This mixture of estrogen hormones can treat symptoms including hot flashes, night sweats, vaginal dryness and irritation, and prevent osteoporosis.

Premarin can increase your risk of developing heart disease or dementia and should be avoided if you already have these conditions.

Is there a Premarin generic?

Unfortunately, there is currently no generic Premarin available. This is because of the patent granted to the drug maker, preventing generics from being manufactured for a certain period of time after the medication is released. However, if you buy Premarin from a Canadian pharmacy, you can save up to 90% and have your order shipped directly to your door!

Always follow your doctor’s instructions and use Premarin exactly as prescribed.

  • Premarin is usually taken on a daily basis in cycles, such as 3 weeks on follow by 1 week off.
  • Regular physical exams, self-examination for breast lumps, and blood tests are important during Premarin therapy.
  • Do not split Premarin tablets.


Premarin may increase chances of developing endometrial problems that can lead to uterine cancer. To reduce this risk, your doctor might prescribe a progestin drug to take along with Premarin.

Before taking Premarin, inform your doctor if you have:

  • Previously taken Premarin
  • Hysterectomy
  • Seizures
  • Family history of heart attack, stroke, breast cancer, osteoporosis
  • Kidney disease
  • Asthma
  • Diabetes
  • Migraines
  • Thyroid problems
  • Lupus
  • High cholesterol
  • Porphyria

Premarin Side Effects

Common side effects of Premarin include:

  • Diarrhea, nausea, constipation
  • Acne or skin rash
  • Weight gain and increased appetite
  • Headache
  • Leg and back pain

More serious side effects include:

  • Abnormal vaginal bleeding
  • Severe allergic reaction
  • Jaundice
  • Weakness or numbness
  • Breast lumps
  • Swelling in hands or feet


How long do I need to take Premarin for?

Your doctor will determine how long you should take Premarin based on your symptoms, age, and other factors.

Can I stop taking Premarin?

Your doctor may want to taper you off Premarin to avoid unwanted side effects. Talk to your doctor before stopping Premarin on your own.

How is Premarin different from other estrogen therapies?

Premarin contains a mixture of several types of estrogens. It may work better or worse for you than other hormone replacement therapies.

Dr.Heather Bartlett

Medical Content on this page has been reviewed and confirmed for accuracy by

Dr. Heather Bartlett

Dr. Heather Bartlett has been in practice for over 10 years, practicing in outpatient family medicine, emergency medicine, urgent care medicine, and pre-admission testing. After she graduated from Texas A&M College Station, she then enrolled and graduated from St. Matthew’s University School of Medicine, Grand Cayman with a Doctorate of Medicine Degree, in the British West Indies. She is Board Certified Family Medicine, ABFM.

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A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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