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What is Premarin Vaginal Cream?

Premarin Vaginal Cream is a medication containing a mixture of estrogen hormones which is prescribed to treat the vaginal symptoms of menopause such as vaginal irritation, burning, dryness and painful sexual intercourse. Estrogen is necessary for many body processes and Premarin Vaginal Cream works by replacing the estrogen which is normally produced by your body.

Make sure to always read the patient information and instructions before using this medication. Always Follow your doctor’s directions.

• Fill the attached applicator with Premarin Cream.
• Insert the applicator high into your vagina and push down on the plunger to release the medication.
• Clean your applicator with warm soapy water and rinse it well. Do not use hot or boiling water.
• Premarin should be used regularly to get the most benefit from it.
• Tell your doctor if your condition worsens or does not improve.

Tell your doctor and pharmacist:

• About your drug and other allergies.
• If you take any other prescription or over-the counter medications.
• Your medical history particularly of liver disease, blood disorders, blood clots, jaundice, endometriosis, uterine fibroids, asthma, migraines, seizures, porphyria, high or low levels of calcium in your blood, thyroid disorder, kidney disease, gallbladder disease, pancreatic disease, vaginal infections or any other vaginal conditions.
• If you are breast feeding.

You should also know:

• Estrogen vaginal creams may weaken latex or rubber birth control devices including condoms or diaphragms. Talk to your doctor about effective methods of birth control while using Premarin.
• Premarin vaginal cream should not be used if you are pregnant.
• Premarin vaginal cream is not approved to be used by anyone younger than 18.

Common side effects of Premarin include but are not limited to:

• Headaches.
• Pelvic pain.
• Flushing, warmth, redness or a tingly feeling.
• Breast pain.
• Changes to your menstrual periods.

Get medical help if you have any of the following side effects:

• Mental or mood changes including memory loss or depression.
• Breast lumps.
• New or increased vaginal irritation, discharge, itching or odor.
• Unusual vaginal bleeding including spotting, breakthrough bleeding, prolonged or recurring bleeding.
• Severe stomach pain, abdominal pain, nausea or vomiting.
• Jaundice.
• Increased urination or thirst.
• Swelling of your hands, feet or ankles.
• Signs of blood clot problems such as unusual sweating, sudden or severe headache, confusion, weakness on one side of the body, chest pain, jaw pain, left arm pain, slurred speech, trouble breathing, vision changes, leg pain, leg redness, leg swelling, sudden dizziness, fainting or a tingling, weakness or numbness in your arms or legs.
• Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

What should I do if I miss a dose of Premarin?

If you miss a dose of Premarin, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the strength of Premarin Vaginal Cream?

Premarin Vaginal Cream is available in a strength of 0.625mg/g.