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What is Salagen?

Salagen is a prescription medication that is used for dry mouth caused by Sjogren’s syndrome or from saliva gland damage caused by radiation treatments. Salagen contains pilocarpine and works by stimulating certain nerves to increase your saliva production.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Salagen can be taken with or without food.
  • Drink plenty of liquids while taking this medication to prevent dehydration.
  • This medication is most effective when it is taken regularly. Refill your prescription before you run out so there is no pause in your treatment.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications, especially heart medications, blood pressure medications or bronchodilators.
  • Your medical history particularly of asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, other breathing conditions, narrow-angle glaucoma, vision problems, heart disease, kidney disease, liver disease, gallbladder problems or mental illness.
  • If you are pregnant or planning pregnancy.
  • If you are breast-feeding.

You should also know:

  • Salagen can increase sweating making it more likely to become dehydrated. Drink plenty of fluids while taking pilocarpine.
  • This medication may cause blurred vision. Do not drive or operate machinery until you can do it safely.

Side Effects of Salagen

Common side effects of Salagen include but are not limited to:

  • Increased sweating.
  • Increased urination.
  • Headaches.
  • Dizziness.
  • Blurred vision or watery eyes.
  • Chills or flushing.
  • Feeling weak.
  • Nausea or vomiting.
  • Diarrhea.
  • Runny nose.

Get medical help if you have any of the following side effects of pilocarpine.

  • Shortness of breath.
  • Fast or slow heartbeat.
  • Tremors.
  • Severe headache or a pounding in your neck or ears.
  • Lightheadedness.
  • Confusion.
  • Feeling like you might pass out.
  • Symptoms of an allergic reaction such as difficulty breathing, hives, or swelling in your face, lips, or throat.


What should I do if I miss a dose of Salagen?

If you miss a dose of Salagen, you should take it as soon as you remember. However, if it is almost time for your next dose, then skip your missed dose.

What is the strength of Salagen?

Both Salagen and the generic alternative pilocarpine are available in a strength of 5mg.

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