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Saphris (Asenapine) treats medical conditions like mood disorders (schizophrenia, bipolar disorder, etc) by helping patients to think more clearly. It also helps to reduce nervousness, hallucinations, prevent severe mood swings and improve quality of life. It does this by helping to restore the balance of certain neurotransmitters in the brain. This medication belongs to a group of drugs that are classified as atypical antipsychotics.