Seroquel XR is an antipsychotic drug that changes chemical actions in the brain. It is used to treat schizophrenia and bipolar disorder and may be used together with antidepressants to treat the major depressive disorder.

Always follow your doctor’s instructions and use Seroquel XR exactly as prescribed.

• Seroquel XR can be taken with or without food.
• Swallow tablet whole, do not crush or split unless advised by your doctor.

Seroquel XR may increase thoughts of suicide in young people.

Seroquel XR may cause a false positive on a drug screening test.

Seroquel XR is not approved for use in patients with dementia, and may increase risk of death in older adults with dementia.

Tell your doctor if you have:

• Heart, liver, or kidney problems
• High or low blood pressure
• Low white blood cell counts
• Seizures
• High cholesterol

Common side effects of Seroquel XR include:

• Weight gain
• Nausea, upset stomach, constipation, vomiting
• Dry mouth
• Dizziness, weakness
• Sore throat

Contact your doctor if you experience these more serious side effects:

• Uncontrollable muscle movements or twitching
• Low blood cell counts – fever, chills, cough, swollen gums, cold or flu symptoms, mouth or skin sores, trouble breathing, sudden weakness/ill feeling
• Mask-like face, difficulty with speech or swallowing
• High blood sugar – weight loss, increased thirst and urination, hunger, drowsiness, blurred vision
• Blurred/tunnel vision, eye pain, halos
• Nervous system reaction – high fever, stiff muscles, rapid or uneven heartbeat, sweating, confusion, tremors
• Feeling light-headed or passing out

Will Seroquel XR make me gain weight?

Weight gain is one of the most common side effects of Seroquel XR. Changes in diet and increased exercise can help you manage this weight gain.

What’s the difference between Seroquel and Seroquel XR?

Seroquel XR is an extended release medication. This means it is absorbed more slowly and its effects in the body usually last longer.