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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
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What is Sinemet?

Sinemet, also known as carbidopa-levodopa, is a medication used to treat symptoms of Parkinson’s disease. Levodopa can treat the symptoms of shakiness, stiffness, and difficulty moving. Parkinson’s disease is progressive nervous system disorder that affects movement. This disease is thought to be caused by a lack of dopamine in the brain. Levodopa changes into dopamine in the brain, which helps better control movement.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • Take this drug by mouth with or without food. Taking Sinemet with food may decrease feelings of nausea.
  • This drug is typically taken 3 to 4 times a day.
  • These drugs come in many different strengths of levodopa and carbidopa, so make sure you have the correct strength of both drugs.
  • Carbidopa may also be prescribed alone along with Sinemet.
  • Use this drug regularly to get the most benefit from it.
  • In some patients, a feeling of worsening symptoms may occur before the next dose, resulting in feelings of stiffness. Tell your doctor if this occurs often.
  • Do not stop taking this medication without consulting your doctor.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • If you have a medical history of liver disease, glaucoma, breathing problems, heart disease, stomach ulcers, mood disorders, blood disorders, seizures, or sleep disorders.
  • If you are pregnant or breast-feeding. This drug is used during pregnancy when clearly needed.

You should also know:

  • Levodopa passes into breast milk and can affect how much milk a woman produces.
  • Consuming alcohol or cannabis may increase the side effects of dizziness or drowsiness.

Side effects of Sinemet

Common side effects of Sinemet include but are not limited to:

  • Dizziness
  • Lightheadedness
  • Nausea
  • Vomiting
  • Loss of appetite
  • Trouble sleeping
  • Unusual dreams
  • Headache
  • Darkening or saliva, urine, or sweat - this side effect is harmless, but can stain clothes

Get medical help if you have any of the following side effects of carbidopa-levodopa.

  • Increased eye blinking, twitching
  • Eye pain or vision changes
  • Severe stomach pain
  • Black or tarry stools
  • Depression
  • Hallucinations
  • Easy bruising or bleeding
  • Unusual tiredness
  • Irregular heartbeat
  • Rapid breathing


Do any drugs interact with Sinemet?

It is vital to separate your dose of Sinemet by as many hours as possible from any iron supplements, like vitamin supplements. Iron can reduce the amount of medication absorbed by the body. Tell your doctor if you take supplements that contain iron.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

Real Customers, Honest Reviews

I have had good experiences with RX Connected. Rich
Richard February 28, 2020

Real Customers, Honest Reviews

I placed my first order last November. The process is exactly as I was told. I emailed my information, and sent original copies to them. Every time I have refilled my medication the representative has been friendly,and knowledgeable. I called today inquiring about the current status of a refill. After a short time, the representative gave me the information I needed (so I wouldn't worry). I appreciate the savings, and the professionalism shown by all the employees I've had contact with via phone. Keep up the good work.
Alex February 27, 2020

Real Customers, Honest Reviews

Like most other people, my prescription was very expensive and not covered. I started looking and found this pharmacy. While it takes approximately a month to receive your script, it's worth it for the savings.
Margaret February 26, 2020

Real Customers, Honest Reviews

In the past, I had heard people talk about getting some of their prescriptions from Canada due to the high prices in the US. I never really considered it until after a local doctor suggested RX Connected for one of my recommended medications. The price for the medication here was very expensive and not covered by by Medicare drug supplement plan. I'm very grateful that he told me about RX Connected. I have since told several other people about RX Connected. After your doctor writes the initial prescription, you just send it in, and the process begins. They are careful, professional, and send me my medication by mail, on time, like clock-work. Thank you RX Connected!
Judy February 25, 2020

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Always very polite and helpful. I appreciate so much the reminders when it's time to renew my prescription! Thank you!
Betty February 21, 2020

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great thanks
Helen February 21, 2020

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Sheffield February 21, 2020

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Great service.
Joe February 21, 2020

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Patricia February 21, 2020

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Easy process and reasonable pricing . Both good reasons to use this company .
Terry October 25, 2019
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