Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
  • Delivery time is between 8-14 business days.
  • Express shipping may be available upon request;
Available 7 Days a Week


Express shipping

May be available opon request;

Lowest Price, Guaranteed

match price or beat it by 10% *

Life-Time Free shipping

Find out if you're eligible!

Buy Synthroid (Levothyroxine) Online

RXConnected is a safe, affordable online pharmacy which makes ordering Canadian drugs such as Synthroid hassle free. We can help you to save  up to 90% on the cost of your medications. Buy Synthroid online from our Canadian pharmacy today!

What is Synthroid?

Synthroid is used to treat thyroid conditions, and replaces a hormone produced by the thyroid. This drug can be used to treat hypothyroidism or to prevent goiter caused by hormone imbalances, cancer, or radiation treatment. Taking Synthroid can relieve symptoms including poor growth, constipation, weight gain, slow speech, hair loss, lack of energy, excessive tiredness, dry or thick skin, increased sensitivity to cold, muscle and joint pain, heavy or irregular menstrual periods and depression. Levothyroxine works by replacing the thyroid hormone usually produced by the body.

Always follow your doctor’s instructions and use Synthroid exactly as prescribed.

  • Take on an empty stomach, between 30 and 60 minutes before your first meal.
  • Swallow Synthroid whole with a full glass of water.
  • If you cannot swallow tablets whole, crush synthroid and mix it into one or two teaspoons of water.
  • Synthroid may take several weeks to show symptom relief, and should not be discontinued unless advised by your doctor.


Synthroid is not a weight loss drug or obesity treatment. Taking it alongside appetite suppressants or weight loss drugs may be dangerous.

Before taking Synthroid, inform your doctor if you have any of the following:

  • Thyrotoxicosis
  • Heart attack symptoms
  • Adrenal gland disorders
  • Diabetes
  • Heart or kidney disease
  • Osteoporosis
  • Allergies

Low thyroid levels can be dangerous during pregnancy, but your doctor may need to change your dose if you become pregnant.

Some dietary supplements and medications interfere with Synthroid. Take other medications 4 hours before or after Synthroid.

Side Effects of Synthroid

Common side effects of Synthroid include:

  • Headache
  • Muscle weakness
  • Leg cramps
  • Diarrhea
  • Skin rash or hair loss
  • Tremors and nervousness

More serious side effects include:

  • Chest pain, shortness of breath, irregular heart rate
  • Hair loss, dry skin and hair
  • Fever or sweating
  • Irritability
  • Vomiting, diarrhea, appetite changes
  • Changes in menstrual period


Can I take other drugs at the same time as Synthroid?

Iron supplements (including multivitamins with iron), calcium supplements and antacids can all interfere with Synthroid. Take these 4 hours before or after Synthroid, and check with your doctor about any other medication you take.

If I get pregnant, should I stop taking Synthroid?

Hypothyroidism can lead to complications during pregnancy, including miscarriage, low birth weight, and stillbirth. Don’t stop taking Synthroid if you get pregnant, and talk to your doctor about your Synthroid dose.

Real Customers, Trustworthy Reviews

Some frequently asked questions
A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.