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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
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What is Tofranil?

Tofranil, also known as imipramine, is a medication used to treat depression. This drug is often used in combination with other therapies for the treatment of bed-wetting in children. Imipramine is used to improve mood, sleep, appetite, and energy level. Imipramine is a tricyclic antidepressant that helps restore the balance of natural substances, like norepinephrine, in the brain.

How does Tofranil treat bed-wetting?

Imipramine aids in the treatment of bed-wetting in children by blocking the effect of acetylcholine (a natural substance in the body) in the bladder.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

  • This drug is taken by mouth with or without food.
  • Tofranil is typically taken 1-4 times a day. If you experience drowsiness taking this drug, your doctor may direct you to take the entire dose once at bedtime.
  • When used in children for bed-wetting, this drug should be taken an hour before bed. If your child wets the bed earlier in the night, you may separate the drug into a dose in the afternoon as well.
  • Continue taking this medication even if you feel well.
  • This drug may not work as well if children take this drug for an extended period of time. Talk to your doctor if the medication stops working.


Tell your doctor and pharmacist:

  • About your drug and other allergies.
  • If you take any other prescription or over-the-counter medications.
  • If you have a medical history of breathing problems, eating disorders, liver problems, mood disorders, seizures, brain injury, certain types of tumors (neuroblastoma), or overactive thyroid.
  • Imipramine may cause a heart rhythm condition called QT prolongation, which may result in irregular heartbeat symptoms. Low levels of potassium may increase these risks.
  • If you have diabetes because this drug may make it harder to control your blood sugar.
  • If you are pregnant or breast-feeding.

You should also know:

  • Consuming alcohol or cannabis may increase side effects of dizziness or drowsiness.
  • Older adults may be more sensitive to the side effects of this drug.
  • This drug can be used during pregnancy when needed, but imipramine DOES pass into breast milk and could have undesirable effects on a nursing infant.

Side effects of Tofranil

Common side effects of Tofranil include but are not limited to:

  • Dry mouth
  • Blurred vision
  • Headache
  • Drowsiness
  • Dizziness
  • Constipation
  • Nausea or vomiting
  • Weight gain or loss
  • Stomach cramps

Get medical help if you have any of the following side effects of imipramine.

  • Mood changes
  • Enlarged or painful breasts
  • Unusual breast milk production
  • Ringing in the ears
  • Decreased sexual ability
  • Numbness or tingling in the hands or feet
  • Trouble urinating
  • Tremors


How long does Tofranil take to work?

Tofranil does not work right away. It can take up to 3 weeks before you notice the full effects of this medication for depression. Tell your doctor if your condition does not improve after this amount of time.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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I have had good experiences with RX Connected. Rich
Richard February 28, 2020

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I placed my first order last November. The process is exactly as I was told. I emailed my information, and sent original copies to them. Every time I have refilled my medication the representative has been friendly,and knowledgeable. I called today inquiring about the current status of a refill. After a short time, the representative gave me the information I needed (so I wouldn't worry). I appreciate the savings, and the professionalism shown by all the employees I've had contact with via phone. Keep up the good work.
Alex February 27, 2020

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Like most other people, my prescription was very expensive and not covered. I started looking and found this pharmacy. While it takes approximately a month to receive your script, it's worth it for the savings.
Margaret February 26, 2020

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In the past, I had heard people talk about getting some of their prescriptions from Canada due to the high prices in the US. I never really considered it until after a local doctor suggested RX Connected for one of my recommended medications. The price for the medication here was very expensive and not covered by by Medicare drug supplement plan. I'm very grateful that he told me about RX Connected. I have since told several other people about RX Connected. After your doctor writes the initial prescription, you just send it in, and the process begins. They are careful, professional, and send me my medication by mail, on time, like clock-work. Thank you RX Connected!
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Always very polite and helpful. I appreciate so much the reminders when it's time to renew my prescription! Thank you!
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great thanks
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