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What is Trelegy Ellipta?

Trelegy Ellipta is an inhaled powder used to treat symptoms of COPD. It contains a steroid (fluticasone) to reduce inflammation, along with an anticholinergic (umeclidinium) and bronchodilator (vilanterol) to relax muscles in the airways and improve breathing. Trelegy Ellipta is not a rescue medication, and should not be used to treat asthma.

Always follow your doctor’s instructions and use Trelegy Ellipta exactly as prescribed.

  • Use at the same time daily.
  • Slide open the cover until you hear a click. Exhale fully away from the mouthpiece. Bring Trelegy Ellipta inhaler to your mouth, and inhale deeply. Hold your breath for about 10 seconds then slowly exhale.
  • Rinse mouth with water after use to prevent oral infection.
  • Do not take more than once in a 24 hour period.
  • Keep Trelegy Ellipta inhaler in sealed foil pouch until ready to use. Throw out 6 weeks after opening or once dose indicator shows 0.


Vilanterol may increase the risk of death in people with asthma. The risk of death in people with COPD is unknown. Use Trelegy Ellipta exactly as prescribed by your doctor.

Tell your doctor if you are pregnant, planning pregnancy or breast-feeding.

Trelegy Ellipta is only for use in people with COPD and should not be used to treat asthma.

Before taking Trelegy Ellipta, inform your doctor if you have any of the following:

  • Heart disease, high blood pressure
  • Seizures
  • Any type of infection
  • Diabetes
  • Osteoporosis
  • Thyroid disorder
  • Weak immune system
  • Enlarged prostate or urinary problems

Side Effects of Trelegy Ellipta

Common side effects of Trelegy Ellipta include:

  • Cold or flu symptoms
  • Headache
  • Back pain
  • Joint pain
  • Nausea, vomiting, stomach pain, diarrhea, constipation
  • Mouth pain or changes in taste

Contact your doctor if you experience these more serious side effects:

  • Fever, chills, shortness of breath
  • Increased thirst or urination
  • Pain or difficulty urinating
  • Wheezing, choking, breathing problems
  • Sores or white patches in the mouth
  • Low potassium – constipation, leg cramps, numbness, tingling, muscle weakness, irregular heartbeats, fluttering chest
  • Blurred vision, tunnel vision, eye pain, halos
  • Tremors, chest pain, fast heartbeats


Can I use a spacer with Trelegy Ellipta?

No. Trelegy Ellipta is an inhaled powder, and should not be used with a spacer.

How do I know if I’ve received the proper dose?

When you slide down the cover, you’ll hear a click sound that indicates Trelegy Ellipta is ready to use. You may not taste or feel anything after you inhale your dose.

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March 23, 2023

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A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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