Canadian Pharmacy > Vagifem
DON’T MISS THE Price Drop! For Vagifem (Estradiol)
Please enter a valid Email.

Buy Vagifem

1. Strength


2. Quantity

Vagifem (Estradiol)
QTY Price Unit Price Select
18 $107.00 $5.94 BUY
24 $140.00 $5.83 BUY
36 $205.00 $5.69 BUY
Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-385-5040 and a member of our CareTeam will be happy to assist you.

Call 1-877-385-5040 Questions? Let's Chat
Real Customers, Honest Reviews

Vagifem is a form of estrogen, a female hormone that regulates many functions in the body. This medication is typically prescribed to treat symptoms of menopause including vaginal dryness, irritation, and hot flashes.


Always follow your doctor’s instructions when taking Vagifem. Never change dosage before consulting a healthcare professional.

Vagifem local products may be placed directly into the vagina to treat menopause symptoms including dryness and tissue irritation. Other estrogen products are used to treat systemic symptoms that affect other parts of the body, including hot flashes. Use Vagifem as directed by your doctor to treat your specific symptoms.


Vagifem may increase your chances of developing endometrial cancer (cancer of the uterus). Watch for unusual bleeding and inform your doctor immediately.

Vagifem may also increase your risk of ovarian cancer, stroke, dementia, and blood clots.

When taken with progestin, estrogen products like Vagifem can cause heart disease, stroke, dementia, blood clots, and breast cancer. These risks may depend on how long you use estrogen, and the products should be used for the least amount of time possible.

Vagifem alone does not appear to increase risk of breast cancer when taken for up to 7 years after menopause.

Have regular physical examinations if you take Vagifem for an extended period of time.

Side Effects

Common side effects of Vagifem include:

  • Nausea and vomiting
  • Tender breasts
  • Dizziness and headache
  • Cramps and bloating
  • Changes in libido

More serious side effects of Vagifem include:

  • Abnormal bleeding
  • Heart attack symptoms including chest pain, nausea, shortness of breath
  • Jaundice
  • Pain and swelling of the stomach
  • Breast lump
  • Stroke symptoms including sudden numbness or weakness, problems with vision, speech or balance

What time of day should I use Vagifem?

You can take Vagifem at any time of day that’s convenient for you. Try to take Vagifem at the same time every day.

Will my menopause symptoms go away on their own?

Some menopause symptoms, including hot flashes, are likely to go away on their own. But other symptoms like vaginal dryness may persist due to lack of estrogen. Talk to your doctor about your symptoms and how long you should take Vagifem for.

Can I buy Vagifem over the counter?

No. Vagifem is only available with a prescription at this time.

IMPORTANT NOTE: The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.
IMPORTANT NOTE: Please note that not all medications, including any referenced on this page, are dispensed from our affiliated Canadian pharmacy. The medications in your order may be filled and shipped from an approved International fulfillment center located in a country other than Canada. In addition to dispensing medications from our Canadian pharmacy, medication orders are also filled and shipped from international fulfillment centers that are approved by the regulatory bodies from their respective countries. Medication orders are filled and shipped from approved fulfillment centers around the world including, but not limited to, Canada, Singapore, United Kingdom, New Zealand, Turkey, Mauritius, India, Australia, and the United States. The items in your order may be filled and shipped from any one of the above jurisdictions. The products are sourced from various countries including, but not limited to, Canada, United Kingdom, New Zealand, Turkey, India, Australia, and the United States. All of our affiliated fulfillment centers have been approved by the regulatory bodies from their respective countries.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

What's the difference between generic drugs and brand name drugs?

What's the difference between the branded products you sell and the ones I get locally?
The branded drugs we sell are chemically and therapeutically no different from the ones you get in your local pharmacy. They both generally come from the same exact manufacturer. Generally, the main difference* is in the packaging and the price. Our packaging may be different from what you get locally, but we're also much cheaper.

* Other differences may include differences in trade name, form, and general appearance.

Why are there packaging differences?
Due to differences in government regulation, different countries have different packaging requirements. For example, a product in Canada (or any other country) will have different packaging than the same product in the US even though both drugs are chemically and therapeutically equivalent and are generally manufactured by the same exact company.

Why are your drugs so much cheaper?
Due to government price controls, medications from Canada and many other countries are often significantly cheaper than in the United States. Also, other countries may have more affordable generic versions of drugs, which may not yet be available in the US.

1-877-385-5040 HAVE A QUESTION? CHAT