Vagifem is a form of estrogen, a female hormone that regulates many functions in the body. This medication is typically prescribed to treat symptoms of menopause including vaginal dryness, irritation, and hot flashes.

Always follow your doctor’s instructions when taking Vagifem. Never change dosage before consulting a healthcare professional.

Vagifem local products may be placed directly into the vagina to treat menopause symptoms including dryness and tissue irritation. Other estrogen products are used to treat systemic symptoms that affect other parts of the body, including hot flashes. Use Vagifem as directed by your doctor to treat your specific symptoms.

Vagifem may increase your chances of developing endometrial cancer (cancer of the uterus). Watch for unusual bleeding and inform your doctor immediately.

Vagifem may also increase your risk of ovarian cancer, stroke, dementia, and blood clots.

When taken with progestin, estrogen products like Vagifem can cause heart disease, stroke, dementia, blood clots, and breast cancer. These risks may depend on how long you use estrogen, and the products should be used for the least amount of time possible.

Vagifem alone does not appear to increase risk of breast cancer when taken for up to 7 years after menopause.

Have regular physical examinations if you take Vagifem for an extended period of time.

Common side effects of Vagifem include:

• Nausea and vomiting
• Tender breasts
• Dizziness and headache
• Cramps and bloating
• Changes in libido

More serious side effects of Vagifem include:

• Abnormal bleeding
• Heart attack symptoms including chest pain, nausea, shortness of breath
• Jaundice
• Pain and swelling of the stomach
• Breast lump
• Stroke symptoms including sudden numbness or weakness, problems with vision, speech or balance

What time of day should I use Vagifem?

You can take Vagifem at any time of day that’s convenient for you. Try to take Vagifem at the same time every day.

Will my menopause symptoms go away on their own?

Some menopause symptoms, including hot flashes, are likely to go away on their own. But other symptoms like vaginal dryness may persist due to lack of estrogen. Talk to your doctor about your symptoms and how long you should take Vagifem for.

Can I buy Vagifem over the counter?

No. Vagifem is only available with a prescription at this time.