Voquezna (vonoprazan) is a prescription medication used to treat conditions caused by excess stomach acid, including Helicobacter pylori (H. pylori) infection, erosive esophagitis, and frequent heartburn related to acid reflux. It belongs to a class of drugs called potassium-competitive acid blockers (PCABs), which work by reducing the production of stomach acid. 

Unlike traditional proton pump inhibitors (PPIs), Voquezna acts more quickly and provides longer-lasting acid control, making it a modern option for managing acid-related digestive issues.

What is Voquezna Used For?

Voquezna is a medication used to treat stomach and digestive issues caused by too much acid. It’s often prescribed to help get rid of H. pylori, a type of bacteria that can lead to ulcers. Doctors also use it to treat damage in the esophagus from acid reflux and to relieve frequent heartburn. Voquezna works by lowering the amount of acid your stomach makes, which helps reduce pain and allows your digestive system to heal.

Voquezna (vonoprazan) is available in both 10 mg and 20 mg oral tablet forms, and the correct dosage depends on your specific condition and treatment goals. Always follow your healthcare provider’s instructions when taking this medication, and do not change your dosage without consulting a healthcare professional.

For treating H. pylori infections or erosive esophagitis, Voquezna is often used as part of a combination therapy. In many cases, the higher 20 mg strength is prescribed to ensure effective acid control and healing.

Voquezna 20 mg Tablet

The 20 mg version of Voquezna has recently gained popularity due to its proven effectiveness in managing more severe cases of acid-related disorders. It provides longer-lasting acid suppression, which may help improve healing and symptom relief in patients with persistent or advanced conditions.

If you’re unsure which dose is right for you, talk to your healthcare provider. They’ll evaluate your symptoms and medical history to determine whether the 10 mg or 20 mg strength is the better fit.

Voquezna should be taken exactly as prescribed by your healthcare provider. The tablets are taken by mouth, usually once daily, with or without food. Try to take your dose at the same time each day to maintain consistent levels in your body.

If you are taking Voquezna as part of a combination therapy to treat H. pylori infection, make sure to take all medications in the regimen as directed, even if your symptoms improve before the treatment ends. Completing the full course helps ensure the infection is fully cleared.

Swallow the tablet whole with a glass of water. Do not crush, chew, or split the tablet. If you miss a dose, take it as soon as you remember—unless it’s close to your next scheduled dose. In that case, skip the missed dose and resume your regular schedule. Never double up to make up for a missed dose.

If you have any questions about how to take Voquezna or are experiencing side effects, consult your doctor or pharmacist.

Before starting Voquezna, tell your doctor about any allergies, medical conditions, or other medications you're currently taking. This includes over-the-counter drugs, supplements, and herbal products, as they may interact with Voquezna. Use with caution if you have liver problems or are pregnant or breastfeeding. Always follow your healthcare provider’s instructions to minimize risks and ensure the medication is safe and effective for your condition.

Voquezna Side Effects

Voquezna can cause side effects, including diarrhea, abdominal pain, nausea, and flatulence. These side effects are generally mild and tend to go away once your body gets adjusted to the medication. While rare, more serious side effects—including severe gastrointestinal symptoms or allergic reactions—can occur. If you notice any unusual or concerning side effects, seek medical attention right away.

What should I do if I miss a dose of Voquezna?

If you forget to take your dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up to make up for a missed dose of Voquezna.

Is there a generic version of Voquezna available?

Yes, a generic version of Voquezna (vonoprazan) is available and offered at a significantly lower price. While the brand-name Voquezna costs $1,500.88, the generic vonoprazan 20 mg is available for just $450 for a 100-tablet supply. Both options require a valid prescription.

Why is the generic version of Voquezna so much cheaper?

Generic vonoprazan offers the same active ingredient and therapeutic effect as the brand-name Voquezna but at a fraction of the cost. This is due to reduced marketing and development expenses associated with generics, allowing patients to access effective treatment at a lower price.

Can I buy generic Voquezna from Canada?

Yes, you can order generic Voquezna (vonoprazan) from a licensed Canadian pharmacy like RxConnected. Buying from Canada offers significant savings compared to U.S. pharmacy prices. For example, a 100-tablet supply of generic vonoprazan 20 mg is available for $450, compared to over $1,500 for the brand-name version. 

Can I order Voquezna or its generic online without insurance?

Yes, you can order both brand-name Voquezna and generic vonoprazan from RxConnected without insurance. Simply upload your prescription during checkout. Our prices are set to help patients save—even without coverage.