Vytorin is a prescription drug used to treat high cholesterol. It contains two active ingredients, ezetimibe and simvastatin, that work together to lower levels of triglycerdies and LDL (“bad” cholesterol) and increase HDL (“good” cholesterol).

Always follow your doctor’s instructions and use Vytorin exactly as prescribed.

• Take in the evening, with or without food.
• Use along with exercise and a cholesterol-lowering diet.
• Your doctor will perform frequent blood tests to monitor your progress while taking Vytorin.

Don’t use Vytorin if you’re pregnant or breastfeeding.

Inform your doctor of all other medications you’re taking. Many other prescription drugs interact with Vytorin, including:

• Colcrys (colchicine)
• Tricor (fenofibrate)
• Blood thinners (warfarin, Coumadin, Jantoven)
• Blood pressure and heart medication
• Drugs containing niacin, nicotinic acid, vitamin B3

Grapefruit contains an enzyme that can affect how Vytorin is absorbed by your body. Avoid grapefruit products while you’re taking this medication.

Before taking Vytorin, inform your doctor if you have any of the following:

• Liver disease or abnormal liver function tests.
• Thyroid problems
• Kidney disease
• Alcoholism or drinking more than 2 alcoholic beverages per day
• Unexplained muscle pain or weakness

Common side effects of Vytorin include:

• Headache
• Diarrhea
• Muscle pain
• Cold symptoms (stuffy nose, sore throat, sneezing)

Contact your doctor if you experience these more serious side effects:

• Jaundice
• Dark urine
• Fever or fatigue
• Muscle pain, tenderness, weakness
• Upper abdominal pain

Can I drink alcohol while taking Vytorin?

Drinking alcohol while taking Vytorin can raise triglyceride levels and increase your risk of liver damage. Check with your doctor before consuming alcohol while taking Vytorin.

What is a cholesterol-lowering diet?

A cholesterol-lowering diet typically involves eating fewer sources of saturated and trans fats (full-fat dairy, fatty and processed meats, packaged snacks and pastries). Eat fewer processed foods, more vegetables, and sources of fiber like whole grains and vegetables. For complete cholesterol-lowering meal plans, your doctor may recommend a consultation with a nutritionist or dietitian.