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Zestoretic is a combination medicine Lisinopril + HCTZ) used to treat high blood pressure. It contains an ACE inhibitor (lisinopril) that relaxes blood vessels and a diuretic (hydrochlorothiazide) that prevents the body from absorbing too much salt.
Always follow your doctor’s instructions and use Zestoretic exactly as prescribed.
Don’t use Zestoretic if you are pregnant or breastfeeding.
Do not use Zestoretic if you’re allergic to sulfa drugs, are unable to urinate, or have ever had angioedema.
Wait at least 36 hours between taking Zestoretic and any medicine containing sacubatril.
If you have diabetes, do not take Zestoretic together with medications that contain aliskiren (Tekturna, Tekamlo).
Before taking Zestoretic, inform your doctor if you have any of the following:
Common side effects of Zestoretic include:
Contact your doctor if you experience these more serious side effects:
Can I drink alcohol while taking Zestoretic?
Drinking alcohol can lower your blood pressure, and may increase side effects of Zestoretic like dizziness and tiredness. Use alcohol carefully and inform your doctor of any adverse effects.