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What is Xarelto?

Xarelto is a prescription blood thinner used to prevent and treat blood clots. It is commonly prescribed for conditions such as deep vein thrombosis, pulmonary embolism, atrial fibrillation not caused by a heart valve problem, and to reduce the risk of blood clots after hip or knee replacement surgery. 

In some patients, Xarelto is also used with low-dose aspirin to reduce the risk of serious heart and circulatory problems associated with coronary artery disease or peripheral artery disease.

Xarelto works by inhibiting Factor Xa, an enzyme involved in blood clotting. For a detailed explanation of how Xarelto works, visit our in-depth article.

Is there a generic for Xarelto?

Yes. The generic name for Xarelto is rivaroxaban.

Generic rivaroxaban has been approved as therapeutically equivalent to brand-name Xarelto. It contains the same active ingredient and is prescribed for the same approved uses.

Generic Xarelto availability: Canada vs. the U.S.

The FDA has approved the generic version of Xarelto, called rivaroxaban. However, availability of certain generic strengths may be limited at U.S. retail pharmacies due to patent, exclusivity, or distribution factors.

Through RxConnected, U.S. patients can order all approved strengths of generic rivaroxaban with a valid prescription. RxConnected works with licensed Canadian and international fulfillment centers, allowing access to generic rivaroxaban even when local U.S. availability is limited.

For patients without insurance, ordering generic rivaroxaban through RxConnected often costs significantly less than purchasing brand-name Xarelto at U.S. retail pharmacies.

The cost of Xarelto in Canada depends on the strength, quantity, and whether you choose the brand-name medication or generic rivaroxaban. Ordering a larger quantity typically lowers the cost per tablet.

Xarelto generic price (rivaroxaban 20 mg):

  • 30 tablets: $77 total (about $2.57 per tablet)
  • 60 tablets: $86 total (about $1.43 per tablet)
  • 90 tablets: $95 total (about $1.06 per tablet)

Brand-name Xarelto 20 mg price:

  • 28 tablets: $120 total (about $4.29 per tablet)
  • 56 tablets: $140 total (about $2.50 per tablet)
  • 84 tablets: $160 total (about $1.90 per tablet)

For patients paying out of pocket, generic rivaroxaban through RxConnected often costs significantly less than brand-name Xarelto purchased at U.S. retail pharmacies. For a detailed breakdown of Xarelto pricing in the United States, see our in-depth pricing guide.

RxConnected also offers Xarelto and rivaroxaban in 2.5 mg, 10 mg, and 15 mg strengths, depending on your prescription.

How to Order Xarelto from RxConnected

Ordering Xarelto or generic rivaroxaban through RxConnected is simple and can be done online or by phone.

  1. Visit RxConnected and enter “Xarelto” into the search bar.
  2. Select your prescribed dosage and quantity, then add the medication to your cart and continue to checkout.
  3. Sign in to your existing account or create a new one. If you prefer to place your order by phone, call 1-877-385-5040.
  4. Upload your valid prescription during checkout or request that we contact your doctor or pharmacy on your behalf.
  5. Confirm your order details and submit your request.
  6. Once approved, your medication is dispensed by a licensed pharmacy and shipped directly to your home.

Xarelto Uses, Side Effects, Cautions

Xarelto Uses, Side Effects, Cautions

How to take Xarelto

Take Xarelto exactly as prescribed by your healthcare provider. The dosage and strength depend on your medical condition and treatment plan. Xarelto is available in 2.5 mg, 10 mg, 15 mg, and 20 mg tablets.

Do not stop taking Xarelto suddenly without medical guidance, as stopping abruptly can increase the risk of blood clots or stroke.

Cautions

Avoid taking other anti-coagulants or NSAIDs (aspirin, ibuprofen, naproxen) unless directed by your doctor. These can increase the risk of bleeding.

Before taking Xarelto, inform your doctor if you have:

  • Bleeding disorders or a history of stroke
  • Spinal defects, history of spinal surgery, or recent spinal tap/catheter
  • Take NSAID drugs or other anti-coagulant drugs
  • High blood pressure
  • Liver or kidney disease
  • Pregnant or breastfeeding

Xarelto side effects

Common side effects of Xarelto include:

  • Headache
  • Dizziness
  • Back and muscle pain

Xarelto increases your risk of bleeding. Contact your doctor if you have any of the following:

  • Bloody or black stools
  • Bleeding gums
  • Coughing up blood
  • Nosebleeds
  • Red or dark brown urine
  • Vomiting blood
  • Cuts or wounds that won’t stop bleeding

FAQs

Why does Xarelto cost so much in the U.S.?

Xarelto is a brand-name medication, and U.S. drug prices are not regulated, which often leads to high retail costs. Patients without insurance may face significant out-of-pocket expenses. 

Ordering from an online Canadian pharmacy like RxConnected can help reduce costs by connecting patients with lower-priced options that ship directly to their homes. For a closer look at why Xarelto costs so much in the U.S. and what options may help lower those costs, see our detailed pricing guide.

Is there a generic for Xarelto?

Yes. The generic version of Xarelto is called rivaroxaban. It contains the same active ingredient as brand-name Xarelto.

How much is Xarelto in Canada?

The cost of Xarelto in Canada depends on the dosage, quantity, and whether you choose brand-name Xarelto or the generic version, rivaroxaban.

  • For generic rivaroxaban 20 mg, a 30-tablet supply costs about $77, while a 90-tablet supply costs about $95, which reduces the per-tablet cost.
  • For brand-name Xarelto 20 mg, a 28-tablet supply costs about $120, and an 84-tablet supply costs about $160.

Ordering larger quantities typically lowers the per-tablet cost for patients paying out of pocket.

Can I order Xarelto from Canada?

Yes. U.S. patients can order Xarelto or generic rivaroxaban through RxConnected with a valid prescription. Medications are dispensed by licensed pharmacies and shipped to your home.

What is the cost of Xarelto without insurance?

Without insurance, Xarelto can be expensive in the United States. A 56-tablet supply of Xarelto 20 mg costs about $1,104 at U.S. retail pharmacies. Through an online Canadian pharmacy like RxConnected, the same dosage and quantity costs about $140. Patients seeking to further reduce costs may choose generic rivaroxaban, which costs about $86 for 60 tablets of 20 mg.

What is the cheapest price for Xarelto?

The lowest per-tablet price is usually achieved by ordering generic rivaroxaban in higher quantities. For example, a 90-tablet supply of rivaroxaban 20 mg offers one of the lowest per-tablet costs available.

Do I need a prescription to order Xarelto online?

Yes. A valid prescription from a licensed healthcare provider is required to order Xarelto or generic rivaroxaban through RxConnected.

Does Xarelto come with any dietary restrictions?

Xarelto does not require special dietary restrictions like some older blood thinners. However, grapefruit should be avoided because it may increase Xarelto levels in the blood.

What if I run out of Xarelto?

Stopping Xarelto suddenly can increase the risk of blood clots or stroke. It is important to refill your prescription on time and speak with your healthcare provider if you miss a dose.

What if I’m going to have dental surgery?

Tell your doctor and dentist before any dental procedure. Your healthcare provider may adjust your Xarelto dosing temporarily to reduce the risk of excessive bleeding.

Dr.Heather Bartlett

Medical Content on this page has been reviewed and confirmed for accuracy by

Dr Heather Bartlett

MD

Dr. Heather Bartlett has been in practice for over 10 years, practicing in outpatient family medicine, emergency medicine, urgent care medicine, and pre-admission testing. After she graduated from Texas A&M College Station, she then enrolled and graduated from St. Matthew’s University School of Medicine, Grand Cayman with a Doctorate of Medicine Degree, in the British West Indies. She is Board Certified Family Medicine, ABFM.

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A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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